What is CBD?
Cannbidiol (CBD) is one of over 113 compounds found in cannabis that belong to a class of ingredients called cannabinoids. Until recently, THC was getting most of the attention because it’s the ingredient in cannabis that produces mind-altering effects in users, but CBD is also present in high concentrations – and the medical world is realizing that its list of medical benefits continues to grow.
CBD is the major non-psychoactive component of Cannabis sativa. According to a 2013 study published in the British Journal of Clinical Pharmacology, CBD benefits in some experimental models as an anti-inflammatory, anticonvulsant, antioxidant, antiemetic, anxiolytic and antipsychotic agent, and is therefore a potential medicine for the treatment of neuroinflammation, epilepsy, oxidative injury, vomiting and nausea, anxiety and schizophrenia.
Research is beginning to show that CBD is different than other well-studied cannabinoids. All cannabinoids act as ligands, meaning they dock onto the binding site of a protein and have the ability to modulate a receptor’s behavior. CB1 receptors are widely distributed, but are particularly abundant in areas of the brain, including those concerned with movement, coordination, pain and sensory perception, emotion, memory, cognition, autonomic and endocrine functions. CB2 receptors are found mostly in the immune system, and they seem to reduce inflammation and certain kinds of pain.
Does the US Goverment have a patent on CBD?
Yes, in fact they do! They patent was granted in 2003 for the potential neuroprotective and antioxidant properties of CBD. U.S. Patent 6630507
Cannabinoids as antioxidants and neuroprotectants
Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and HIV dementia. Nonpsychoactive cannabinoids, such as cannabidoil, are particularly advantageous to use because they avoid toxicity that is encountered with psychoactive cannabinoids at high doses useful in the method of the present invention. A particular disclosed class of cannabinoids useful as neuroprotective antioxidants is formula (I) wherein the R group is independently selected from the group consisting of H, CH.sub.3, and COCH.sub.3. ##STR1##
|Inventors:||Hampson; Aidan J. (Irvine, CA), Axelrod; Julius (Rockville, MD), Grimaldi; Maurizio (Bethesda, MD)|
|Assignee:||The United States of America as represented by the Department of Health and Human Services (Washington, DC)|
|Filed:||February 2, 2001|
|PCT Filed:||April 21, 1999|
|PCT Pub. No.:||WO99/53917|
|PCT Pub. Date:||October 28, 1999|
Should I take CBD Hemp Oil?
We recommend that an individual speak to their health care provider before taking any supplement. We do not claim that our products diagnose, treat, cure and/or prevent any medical condition, disease or illness. Finally, we do not offer medical advice regarding our products or the consumption thereof. Please speak to your health care provider on what is best suited for you and your specific health conditions.
Is Pure Innate's products THC Free?
Yes! Our CBD Oil is THC free. We analyze levels of Cannabinoids in the hemp extract and PRC CBD Oil. We perform 3rd party lab testing to guarantee there is 0.0% THC.
What Conditions is CBD being used for?
Pure Innate is making no claims or treatment suggestions, but CBD has been used to treat many conditions, below are some of them:
Among common CBD benefits natural pain relief tops the list for many. Evidence suggests that cannabinoids may prove useful in pain modulation by inhibiting neuronal transmission in pain pathways. A 2012 study published in the Journal of Experimental Medicine found that CBD significantly suppressed chronic inflammatory and neuropathic pain in rodents without causing analgesic tolerance. Researchers suggest that CBD and other nonpsychoactive components of marijuana may represent a novel class of therapeutic agents for the treatment of chronic pain.
Research shows that CBD benefits include producing antipsychotic effects. It appears to have a pharmacological profile similar to that of atypical antipsychotic drugs as seen using behavioral and neurochemical techniques in animal studies.
Cannabidiol has shown to reduce anxiety in patients with social anxiety disorder, and researchers suggest that it may also be effective for panic disorder, OCD, and post-traumatic stress disorder.
Several scientific reports demonstrate that CBD benefits include possessing antiproliferative, pro-apoptotic effects that inhibit cancer cell migration, adhesion and invasion. Not only does the research show that CBD benefits including being effective in fighting breast cancer cells, data also suggests that it can be used to inhibit the invasion of lung and colon cancer, plus it possesses anti-tumor properties in gliomas and has been used to treat leukemia.
Cannabis has been used for centuries for the suppression of nausea and vomiting. A 2014 survey conducted by researchers at Stanford University was presented to parents belonging to a Facebook group dedicated to sharing information about the use of cannabidiol-enriched cannabis to treat their child’s seizures. A 2006 study found that CBD treatment significantly reduced the incidence of diabetes in non-obese diabetic mice from an incidence of 86 percent in non-treated mice to an incidence of 30 percent in CBD-treated mice.
A 2013 study published in the British Journal of Clinical Pharmacology reports that CBD protects against the vascular damage caused by a high glucose environment, inflammation or the induction of type 2 diabetes in animal models; plus, CBD proved to reduce the vascular hyperpermeability (which causes leaky gut) associated with such environments.
Will I fail a drug test?
Most workplace drug screens and tests target delta9-tetrahydrocannabinol (THC) and do not detect the presence of Cannabidiols or other legal natural hemp based constituents.
Many other products sold on the market have THC levels of .3% which is legal to sell by law in all 50 states. However, our product is certified and guaranteed to be FREE of THC.
While we can’t guarantee that after ingesting our products you will not fail a drug test you can rest assured that our products have zero THC.
There are some tests that may give a false positive, even with Zero THC. Typically if this happens additional testing using mass spectrometry is performed to rule out a false positive test.
If you are required to take workplace drug tests, we advise you do not take our product.
Is CBD oil a cure?
Because our CBD hemp oil products are categorized as dietary supplements in the United States, we comply with the FDA’s DSHEA guidelines and cannot endorse any specific medical benefits of CBD oil. We encourage you to browse the thousands of reputable studies regarding CBD published online and talk with your doctor to see if a CBD supplement is right for you.
What dosage should I take?
This is a difficult question to answer because our customers find differences in their optimal dosage. We suggest you start at a low dose and go up to larger dosing if desired or necessary. Your body will find the daily CBD level that works best for you.
Pure Innate CBD Oil
Pure Innate uses a manufacturing facility that extracts CBD oil from the whole hemp plant. The plants have been grown specifically for their high content of CBD Oil and low THC. This CO2 extraction method that has a “patent pending” squeezes the resin from the plant material using extreme pressure rather than harsh or dangerous solvents.
You can’t improve on pure, natural products that nature created so we avoid anything that compromises the purity and efficacy of our products.